Using Relative Abundance Data to Estimate of Multiplicative Differences in Mean Absolute Abundance


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Documentation for package ‘radEmu’ version 2.3.2.0

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control_fn Create list of control options (to pass to 'emuFit()')
dpseudohuber_median_dx Calculate the derivative to the pseudo-Huber smoothed median
dpsuedohuber_median_dx Calculate the derivative to the pseudo-Huber smoothed median
emuFit Fit radEmu model
emuFit_check Runs checks for appropriate arguments before running 'emuFit()'
emuFit_micro Fit radEmu model. Called by emuFit
emuFit_micro_penalized Fit radEmu model with Firth penalty
fit_null fits model with B_kj constrained to equal g(B_k) for constraint fn g
fit_null_discrete fits model with B_kj constrained to equal g(B_k) for constraint fn g, for a symmetric constraint with a discrete design
fit_null_scc fits model with B_kj constrained to equal g(B_k) for constraint fn g, for a single category constraint
fit_null_symmetric fits model with B_kj constrained to equal g(B_k) for constraint fn g, for a symmetric constraint
fit_null_symmetric_subset fits model with B_kj constrained to equal g(B_k) for constraint fn g, for a symmetric constraint
make_design_matrix Generates the design matrix for a given 'formula' and 'data' object
make_diagnostics_plots makes plots to investigate convergence of estimation under null hypothesis
make_reference_constraints Make lists of constraint functions and their gradients when using a reference taxon
plot.emuFit Plotting function
power_model A fitted GLM model for the power of radEmu to reject a truly false null hypothesis
print.emuFit Print function
pseudohuber_median Calculate the pseudo-Huber smoothed median
psuedohuber_median Calculate the pseudo-Huber smoothed median
score_test Run robust score test
simulate_data Data simulation function
wirbel_otu mOTU table from Wirbel et al. meta-analysis of fecal metagenomes.
wirbel_otu_small subset of mOTU table from Wirbel et al. meta-analysis of fecal metagenomes.
wirbel_sample Covariates from Wirbel et al. meta-analysis of fecal metagenomes.
wirbel_sample_small Covariates from Wirbel et al. meta-analysis of fecal metagenomes, for a subset of samples.
wirbel_taxonomy Taxonomy information for mOTUs from Wirbel et al. meta analysis.