Bayesian Two-Stage Design with Window-Cohort and Controlled Roll-on for Time-to-Event Estimand


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Documentation for package ‘WCRBayesDesign’ version 1.0.1

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conduct Bayesian Interim and Final Analysis (Unified Transformed Time Framework)
delta_from_theta_goal Convert target EFS goal to delta parameter under proportional hazards model
find_Nw_pIA Search for feasible interim analysis thresholds (Unified Framework)
oc_two_stage Evaluate operating characteristics for two-stage adaptive survival designs (Unified Framework)
run_two_stage_trial Run Two-Stage Bayesian Single-Arm Survival Trial Simulation
S0_inverse Inverse of baseline survival function S_0
S0_weibull Weibull reference survival function
stats_transformed Compute transformed statistics for survival data
two_stage_optimize_design Optimize two-stage adaptive survival design