SAVER (Single-cell Analysis Via Expression Recovery) implements a regularized regression prediction and empirical Bayes method to recover the true gene expression profile in noisy and sparse single-cell RNA-seq data.
You can install SAVER from CRAN by running:
install.packages("SAVER")
library(SAVER)You can also install the most recent updates of SAVER from github with:
# install.packages("devtools")
devtools::install_github("mohuangx/SAVER")For more information about the method, check out the website, tutorial, and paper.