adoptr: Adaptive Optimal Two-Stage Designs

Optimize one or two-arm, two-stage designs for clinical trials with respect to several implemented objective criteria or custom objectives. Optimization under uncertainty and conditional (given stage-one outcome) constraints are supported. See Pilz et al. (2019) <doi:10.1002/sim.8291> and Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09> for details.

Version:	1.1.1
Imports:	nloptr, methods, glue
Suggests:	knitr, rmarkdown, testthat, covr, rpact, vdiffr, pwr, dplyr, ggplot2, tidyr, gridExtra, bookdown
Published:	2024-10-02
DOI:	10.32614/CRAN.package.adoptr
Author:	Kevin Kunzmann [aut, cph], Maximilian Pilz [aut, cre], Jan Meis [aut], Nico Bruder [aut]
Maintainer:	Maximilian Pilz <maximilian.pilz at itwm.fraunhofer.de>
BugReports:	https://github.com/optad/adoptr/issues
License:	MIT + file LICENSE
URL:	https://github.com/optad/adoptr, https://optad.github.io/adoptr/
NeedsCompilation:	no
Citation:	adoptr citation info
Materials:	README NEWS
CRAN checks:	adoptr results

Documentation:

Reference manual:	adoptr.pdf
Vignettes:	Get started with adoptr (source, R code) The adoptr Package: Adaptive Optimal Designs for Clinical Trials in R (source, R code) Composite Scores (source, R code) Conditional Scores and Constraints (source, R code) Defining New Scores (source, R code) Designs for non-normal Endpoints with approximately normal test statistics (source, R code) Working with priors (source, R code)

Downloads:

Package source:	adoptr_1.1.1.tar.gz
Windows binaries:	r-devel: adoptr_1.1.1.zip, r-release: adoptr_1.1.1.zip, r-oldrel: adoptr_1.1.1.zip
macOS binaries:	r-devel (arm64): adoptr_1.1.1.tgz, r-release (arm64): adoptr_1.1.1.tgz, r-oldrel (arm64): adoptr_1.1.1.tgz, r-devel (x86_64): adoptr_1.1.1.tgz, r-release (x86_64): adoptr_1.1.1.tgz, r-oldrel (x86_64): adoptr_1.1.1.tgz
Old sources:	adoptr archive

Reverse dependencies:

Reverse depends:

adestr

Linking:

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