tci: Target Controlled Infusion (TCI)

Implementation of target-controlled infusion algorithms for compartmental pharmacokinetic and pharmacokinetic-pharmacodynamic models. Jacobs (1990) <doi:10.1109/10.43622>; Marsh et al. (1991) <doi:10.1093/bja/67.1.41>; Shafer and Gregg (1993) <doi:10.1007/BF01070999>; Schnider et al. (1998) <doi:10.1097/00000542-199805000-00006>; Abuhelwa, Foster, and Upton (2015) <doi:10.1016/j.vascn.2015.03.004>; Eleveld et al. (2018) <doi:10.1016/j.bja.2018.01.018>.

Version: 0.1.2
Depends: R (≥ 3.6.0)
Imports: ggplot2, stats, utils, truncnorm, mvtnorm, gridExtra, reshape, Rcpp
LinkingTo: Rcpp, RcppArmadillo
Suggests: testthat (≥ 2.1.0), knitr, rmarkdown, mrgsolve
Published: 2021-11-04
Author: Ryan Jarrett [aut, cre]
Maintainer: Ryan Jarrett <ryan.t.jarrett at vanderbilt.edu>
BugReports: https://github.com/jarretrt/tci/issues
License: GPL-2
URL: https://github.com/jarretrt/tci
NeedsCompilation: yes
Materials: README
CRAN checks: tci results

Documentation:

Reference manual: tci.pdf
Vignettes: Illustration of open- and closed-loop control
Introduction to tci package
Simulation from a user-specified, ODE-based PK model

Downloads:

Package source: tci_0.1.2.tar.gz
Windows binaries: r-devel: tci_0.1.2.zip, r-devel-UCRT: tci_0.1.2.zip, r-release: tci_0.1.2.zip, r-oldrel: tci_0.1.2.zip
macOS binaries: r-release (arm64): tci_0.1.2.tgz, r-release (x86_64): tci_0.1.2.tgz, r-oldrel: tci_0.1.2.tgz
Old sources: tci archive

Linking:

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